66) The "immunotolerance" of a pregnant woman toward her unborn child is the result of
A) the tenacity with which the unborn child's immune system counteracts the woman's immune system.
B) the relative quiescence of a pregnant woman's immune system compared to when she was not pregnant.
C) the complete physical separation of her cells from those of the unborn child.
D) the unborn child having enough of the woman's identity so as to escape detection as foreign.
E) modern medical intervention during every pregnancy.
Hirsutism is a bothersome hyperandrogenic manifestation of PCOS that may require at least six months of treatment before improvement begins. According to a 2015 Cochrane review, the most effective first-line therapy for mild hirsutism is oral contraceptives. 32 Spironolactone, 100 mg daily, and flutamide, 250 mg twice daily, are safe for patient use, but the evidence for their effectiveness is minimal. 32 Other therapies include eflornithine (Vaniqa), electrolysis, or light-based therapies such as lasers and intense pulsed light. Any of these can be used as monotherapy in mild cases or as adjunctive therapy in more severe cases. 33
Polycystic ovary syndrome (PCOS) is recognized as one of the most common endocrine/metabolic disorders in women. Its prevalence depends in part upon the diagnostic criteria used to define the disorder [ 4 ]. As an example, in a report of 827 women with World Health Organization (WHO) class II oligoovulation (euestrogenic normogonadotropic ovulatory dysfunction), 456 (55 percent) were classified as having PCOS by the National Institutes of Health (NIH) 1990 criteria (irregular menses, biochemical and/or clinical hyperandrogenism, and other causes of hyperandrogenism excluded).