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So glad I found your site after reading all the other alarming information. I was diagnosed a year ago with LS, but everyone has talked of Gynaecologist referals so how come I ended up in Dermotology? What worries me are the lumps & bumps which are referred to and which I have plus blisters. Help is this normal? I am using an emulent based cream for washing & barrier protection & a stronger steriod cream (as the first cream didn’t work, but having said that, was I not using enough, as they say sparingly!) How do you know if you are reacting to the creams etc with this problem? How demoralised I feel as a woman who looked forward to & shortly enjoyed the freedom of sex after her hysterectomy to now not being able to have sex. (Sorry feeling low). Its also funny that after the ‘op’ I started swimming again & it is said that clorine can affect you, it was a few months after when problems started together with a reaction to 2 medications really kick started it. I also have read that you can be alergic to ‘sperm fluid’ is this then also another starting point after the ‘op’ since previous protection used?
Butoconazole nitrate has no apparent adverse effect when administered orally to pregnant rats throughout organogenesis at dose levels up to 50 mg/kg/day (5 times the human dose based on mg/m²). Daily oral doses of 100,300 or 750 mg/kg/day (10,30 or 75 times the human dose based on mg/m² respectively) resulted in fetal malformations (abdominal wall defects, cleft palate ), but maternal stress was also evident at these higher dose levels. There were, however, no adverse effects on litters of rabbits who received butoconazole nitrate orally, even at maternally stressful dose levels (., 150 mg/kg, 24 times the human dose based on mg/m²).