In 2002, researchers at The Randall Division of Cell and Molecular Biophysics determined the structure of IgE.  Understanding of this structure (which is atypical of other isotypes in that it is highly bent and asymmetric) and of the interaction of IgE with receptor FcεRI will enable development of a new generation of allergy drugs that seek to interfere with the IgE-receptor interaction. It may be possible to design treatments cheaper than monoclonal antibodies (for instance, small molecule drugs) that use a similar approach to inhibit binding of IgE to its receptor.
Prognosis for patients with autoimmune hepatitis is varied, depending on their age, sex and lifestyle. Women and young girls are more likely to suffer from the disease than men. Corticosteroids and immunosuppressants have been used effectively in arresting the progress of autoimmune hepatitis in some patients. There are cases where the disease has eventually resulted in cirrhosis of the liver, leading to irreversible liver failure. Such patients can survive only with a liver transplant. Anti smooth muscle antibodies test can help in the early diagnosis and treatment of autoimmune hepatitis so that patients can live longer with a healthier lifestyle.
Allergic and other hypersensitivity reactions to foods and aeroallergens are characterized by elevated allergen-specific antibody levels in the affected
individual’s blood. Research indicates that these types of reactions are implicated in a number of health problems. Through our Enzyme Linked
Immunosorbent Assay ( ELISA ) & Chemiluminescence methodology we provide a useful tool for
practitioners to assess their patients’ allergies and sensitivities to a variety of common allergens.
Our standard, curve based method for our semi-quantitative allergen-specific IgE ELISA & quantitative Chemiluminescence is traceable to World Health Organization’s standards. These standards increase immunoassay sensitivity against a broad range of allergen concentrations allowing for the detection of minute levels of IgE antibodies in a serum specimen for accurate assay performance. This respect for global standards and attention to detail guarantees the highest quality antibody testing for your patients.
For a comprehensive look at the body’s immune reaction to foods and inhalants, US BioTek Laboratories offers the following antibody assays: