Antenatal steroids risks

Hi. I'm not pregnant but am asking a question on behalf of my daughter. She is being monitored very closely as we were told 4 weeks ago that baby is a "bit on the small side". She is 32 weeks 4 days pregnant & baby hasn't put any weight on/ grown since her last scan two weeks ago. She weighs . At her scan yesterday they also told her that her baby's lungs were under developed and she had a steroid injection with another planned for today. She has a elected for a planned c - section because she suffered pelvic & serious head injuries in a car crash years ago so the consultant is playing safe. I've read about steroid injections preventing early labour with some ladies but so far my daughter hasn't shown any sign of early labour. Just wondered if any one had had a similar issue but went on ti go full term & if the steroids worked etc
Sorry for the long post but we weren't even sure my daughter could conceive so everyday she carries my grand daughter is a little miracle. Zx

One recent randomized controlled trial showed a significant reduction in IVH with antenatal corticosteroid treatment. Secondary outcome variables reported in the meta-analysis of randomized controlled trials also showed a significant reduction in the incidence of IVH with an odds ratio of (95% CI -). This reduction in IVH is supported by the results of the observational database, information prospectively collected in five registries involving more than 30,000 low-birthweight infants. Since IVH is an important contributor to mortality and serious long-term neurodevelopmental disability, this reduction is a major benefit.

In a multicentre RCT with 651 infants, Kendig et al [51] showed that there was no clinically significant difference in outcome between immediate administration of prophylactic surfactant and administration at 10 min after birth after a brief period of stabilization (evidence level 1b). However, giving the surfactant as soon as possible once stabilization has occurred seems to be important. The open study of infants at high risk of or with respiratory insufficiency – the role of surfactant (OSIRIS) [52] demonstrated that the combined incidence of death or BPD was reduced by about 11% when surfactant was given at a mean postnatal age of 2 h rather than 3 h (RR=, 95% CI to , evidence level 1b), showing that even fairly short delays in therapy worsen outcomes (evidence level 1b).

Antenatal steroids risks

antenatal steroids risks


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